Description

The Protein-DNA Structure-Affinity Database (PDSA) is a database of position weight matrices (PWMs) mapped directly onto the three-dimesional structures of protein-DNA complexes in the PDB. For each protein-DNA complex, the database provides a distribution of binding affinities within a unified coordinate system as described in REFERENCE. In addition, PDSA provides detailed information on the statistics of atomistic interactions between DNA bases and protein residues for each individual protein-DNA complex, as well as global summary information for all protein-DNA complexes in the database. Currently PDSA is restricted to helix-turn-helix motifs, but will be expanded to cover other DNA-binding protein families in the future.

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